BPA-Free Plastics Disrupt Fertility


Published:

Many plastic bottles are sold as “BPA-free”—meaning they don’t contain bisphenol A, an ingredient known to disrupt reproduction in mice. But now it seems that the additives used in place of BPA are potentially just as harmful.

“The discovery could mean that the replacements, such as bisphenol S (BPS), might potentially affect people if they leach out into food or drink.”

There’s no evidence yet that this happens. But the new results from mice suggest that if there is a risk, it may match that posed by BPA itself. “Several of these bisphenols induce changes in the germline similar to those we reported previously for BPA,” says Patricia Hunt of Washington State University in Pullman, who helped draw attention to the BPA problem 20 years ago.

Hunt’s latest discovery emerged in the same way as her BPA findings. As before, she noticed that mice kept in certain plastic cages began to show reproductive problems, such as abnormal eggs and low sperm counts. As with BPA, she found the inner surfaces to which mice were exposed were contaminated, this time with BPS that had leached out from the plastic.

Screening Cells

Hunt investigated the problem in greater detail by exposing female mice fetuses to tiny amounts of a selection of BPA replacements at the point where their eggs are developing. She also exposed male mice to the chemicals just after birth, when they begin developing sperm.

When the exposed mice were older, Hunt screened cells destined to become sperm or eggs for abnormalities. She counted the number of points in DNA—called MLH1 foci—where chromosomes had been reshuffled. The amount of shuffling tallies with the degree of abnormality, with a higher and lower levels of shuffling each being worse in different ways.

Exposed females had abnormally high numbers of MLH1 foci compared to controls—which suggests they will produce more abnormal eggs. The opposite was found in males, possibly causing cells to die before fully maturing into sperm—implying the males would have lower sperm counts. “Our previous studies on BPA showed that these subtle changes increased the frequency of chromosomally abnormal eggs ovulated by adult females, and increased cell death during sperm creation in adult males,” says Hunt.

Oliver Jones at the RMIT University in Melbourne, Australia, cautions that it is too soon for people to worry about the findings. “The number of animals used in the work is very low and the animals themselves were very inbred,” he says. “It should also be remembered that mice are not mini-humans. Some chemicals that cause problems for them don’t affect us as all.”

The abnormalities were passed on for three generations, but faded after that. Hunt stressed that more work is needed to find out if some replacements for BPA might be safer than others, pointing out that there are dozens now in use.

This article was republished from Prevent Disease.

See also:
You’re Probably Drinking Plastic In Your Tap Water
How To Avoid Plastic Today

Source:
Replacement Bisphenols Adversely Affect Mouse Gametogenesis with Consequences for Subsequent Generations

Edit Module
Edit ModuleShow Tags
Edit Module Edit ModuleShow Tags

Daily Astrology

January 18, 2019

Today has several incarnations. The morning hours see high-spirited, joyful moods dominate. The vivacious Gemini Moon is complimented by Venus’ trine to Mars. Social life is pure fun. Mercury’s mid-afternoon conjunction with Pluto can have dark overtones…
Edit ModuleShow Tags

Alternative Health Directory

Browse all listings »

Edit ModuleShow Tags
Edit ModuleShow Tags

Calendar

January 2019

Learn Reiki to awaken your healing hands to care for yourself, your loved ones and pets. Facilitated by Lou Orsan, Reiki Shihan (Master-Teacher) This one-day class covers the basic...

Cost: $150

Where:
Northeast Reiki Center
61 Nicholas Road, Suite B2
Framingham, MA  01701
View map »


Sponsor: Northeast Reiki Center
Telephone: 508-808-5696
Contact Name: Lou Orsan
Website »

More information

This class meets 4 times: January 13th, February 24th, March 24th, April 7th The Eclectic Institute of Aromatherapy and Herbal Studies offers a comprehensive hands-on training in the art and...

Cost: $625 plus a material fee of $50

Where:
Misty Meadows Herbst Center
183 Wednesday Hill Rd
Lee, NH  03861
View map »


Sponsor: Misty Meadow Herbal Center
Telephone: 603-659-7211
Contact Name: Wendy Snow Fogg
Website »

More information

With Amy Bernier In this empowering workshop we will explore the innate intelligence of our gut, “the second brain”. We will use yoga postures and breath work to refine our digestive...

Cost: $40

Where:
State of Grace Yoga and Wellness Center
104 East. Hartford Ave.
Uxbridge, MA  01569
View map »


Telephone: 508-278-2818
Website »

More information

Show More...
Show Less...

Show More...
Show Less...

Show More...
Show Less...

Instructor:  Peyton Pugmire Adult level Come together in a warm and uplifting space to get creative, connect, and breathe! At each meeting, we will have fun making a meaningful craft...

Cost: $45

Where:
Creative Spirit
80 Washington Street
Marblehead, MA  01945
View map »


Sponsor: Creative Spirit
Telephone: 781-797-0389
Contact Name: Peyton Pugmire
Website »

More information

One of the most mysterious and magickal of the archangels, Uriel, has a variety of different and conflicting roles in angelic lore. In The Book of Enoch he is one of humanity’s advocates...

Cost: $45

Where:
Circles of Wisdom
386 Merrimack Street
Suite 1-A
Methuen, MA  01844
View map »


Sponsor: Circles of Wisdom
Telephone: 978-474-8010
Contact Name: Cathy Kneeland
Website »

More information

World famous seminars (www.understandingofmusic.com) turns beginners into musicians, revitalizes and inspires even pro musicians.

Where:
Boston, MA


Telephone: (781) 599-1476
Website »

More information

Show More...
Show Less...

With Sherri Snyder-Roche. This yoga workshop will explore self-compassion, self-love and pushing through discomfort to help your recovery process. Recovery from divorce, eating disorders,...

Cost: $95 for 6 weeks or $17 drop in

Where:
State of Grace Yoga and Wellness Center
104 E. Hartford Avenue, Unit A
Uxbridge, MA  01569
View map »


Telephone: 508-278-2818
Website »

More information

Show More...
Show Less...

Holistic Problem-Solving with Dr. HermanSJr. Tired of missing opportunities that could further your life, your education, even your work? Tired of missing threats that continue to hold back your...

Cost: $100

Where:
Caffe Nero
368 Congress Street
Boston, MA  02210
View map »


Telephone: 321.30.PSYCH(7792)
Contact Name: Soni
Website »

More information

Show More...
Show Less...

Deepen Your Practice DYP-30 Hour Yoga Alliance Course January–May 2019 5 Saturdays, 10am–4pm 1/19, 2/2, 3/30, 4/27, 5/18 Looking to deepen your practice but a 200 Hour training...

Cost: $599

Where:
KJ Fitness
Tewksbury, MA


Sponsor: Relax and Recharge With Chuck
Contact Name: Chuck
Website »

More information

January 19–20 With Patty Collinsworth Weekend class hours: Saturday, 10–5pm and Sunday, 10–5pm Learn how to open the Akashic Records for yourself and others in this...

Cost: $170

Where:
Circles of Wisdom
386 Merrimack Street
Suite 1-A
Methuen, MA  01844
View map »


Sponsor: Circles of Wisdom
Telephone: 978-474-8010
Contact Name: Cathy Kneeland
Website »

More information

The Eclectic Institute of Aromatherapy and Herbal Studies offers a comprehensive hands-on training in the art and science of Aromatherapy. This course covers the...

Cost: $550

Where:
The Soul Purpose
1225 Gar Highway
Swansea, MA  02777
View map »


Sponsor: The Soul Purpose
Telephone: 774-264-1329
Contact Name: Jessica Kozak
Website »

More information

Join nationally known psychic medium/spiritual counselor, Diana Harris, for a mediumship gallery. Diana is a bridge – a conduit between heaven and Earth. Ms. Harris will answer your questions...

Cost: $70

Where:
private office
North Andover, MA  01845


Sponsor: Diana Harris
Telephone: 978-973-6637
Contact Name: Diana Harris
Website »

More information

Holistic Problem-Solving with Dr. HermanSJr. Tired of missing opportunities that could further your life, your education, even your work? Tired of missing threats that continue to hold back your...

Cost: $100

Where:
Caffe Nero
368 Congress Street
Boston, MA  02210
View map »


Telephone: 321.30.PSYCH(7792)
Contact Name: Soni
Website »

More information

Show More...
Show Less...
Edit ModuleShow Tags
Edit Module Edit ModuleShow Tags